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Cefixime Trihydrate Structure

Product Type

API

Grade

BP/USP

Chemical Formula

C16H21N5O10S2 .3H2O

IUPAC Name

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid trihydrate

CAS No.

125110-14-7

Molecular Weight

507.49 g/mol

Chemical Class

Cephalosporins

Therapeutic Class

Antibiotic- Cephalosporins

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to pale yellow crystalline powder
Solubility Poorly soluble in water, slightly soluble in methanol, practically insoluble in ethanol, chloroform, and ether, soluble in dimethylformamide (DMF) and dilute acids
Melting point Decomposes on heating
pH 4.5 to 6.0

Product Description

Cefixime Trihydrate, a broad-spectrum antibiotic, is an orally-active third-generation semisynthetic cephalosporin. Like other cephalosporins, the antibacterial action of Cefixime Trihydrate results from inhibition of cell wall synthesis. Also, like other cephalosporins, Cefixime Trihydrate is stable when in the presence of certain beta-lactamase enzymes, which means certain organisms resistant to penicillin and some cephalosporins due to the presence of beta-lactamases could be susceptible to Cefixime Trihydrate.

How Cefixime Trihydrate Works

Cefixime Trihydrate is a cephalosporin and cephalosporins work by using their beta-lactam rings to inhibit bacterial cell wall synthesis by binding to the penicillin-binding proteins transpeptidases on bacteria. The inhibition of synthesis of the bacteria cell wall will cause lysis, particularly in fast growing organisms such as bacteria. Specifically, cephalosporins inhibit penicillin-sensitive enzymes responsible for the final 3D structure of the bacterial cell wall which in turn inhibit bacterial cell wall peptidoglycan synthesis.

Use(s)

Adverse Effects

Why choose Salius for Cefixime Trihydrate?

  1. Trusted Manufacturing with Global Quality Standards
    Salius complies with WHO-GMP across all facilities, with select sites also approved by the U.S. FDA. Every batch undergoes rigorous laboratory testing to guarantee safety, quality, and full regulatory compliance.
  2. Large-Scale API Production with Competitive Pricing
    Leveraging extensive manufacturing capacity and efficient global distribution, Salius delivers high-quality APIs at competitive prices, supporting pharmaceutical companies in cost-sensitive markets worldwide.
  3. Global Export Expertise and Comprehensive Documentation Support
    Salius has experience exporting APIs worldwide, offering full regulatory documentation including Drug Master Files (DMF) and impurity profiles. We provide dedicated support for regulatory filings to help international clients, even in highly regulated markets, ensure smooth approval and compliance.
  4. Documents We Provide
  5. Proven Reliability
    Salius Pharma is presented as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO-GMP, ISO 9001:2015, FDA-audited facilities
Affordability & Generic Access Cost-competitive generics for global supply
Export Experience Proven record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

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Looking to source Cefixime Trihydrate or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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