API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/USP
C16H24N10O4
bis(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione); ethane-1,2-diamine
317-34-0
420.4264 g/mol
Aminoglycosides
Respiratory Smooth Muscle Relaxants
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Freely soluble in water and alcohol |
| Melting point | 178–183°C |
| pH | 8.8 – 9.2 (alkaline) |
Aminophylline is the ethylenediamine salt of theophylline. Theophylline stimulates the CNS, skeletal muscles, and cardiac muscles. It relaxes certain smooth muscles in the bronchi, produces diuresis, and causes an increase in gastric secretion.
Aminophylline is the ethylenediamine salt of theophylline. After ingestion, theophylline is released from aminophylline, and theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO-GMP, ISO 9001:2015, FDA-audited facilities |
| Affordability & Generic Access | Cost-competitive generics for global supply |
| Export Experience | Proven record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Salius Pharma supplies Aminophylline as a bulk API customized to meet regulatory requirements and market demand across African countries. All products meet WHO-GMP standards and come with complete regulatory documentation.
Aminophylline is widely used as a bronchodilator for managing asthma, chronic bronchitis, and COPD. It helps relieve airway obstruction by relaxing bronchial muscles and improving breathing in patients with respiratory diseases common in this region.
Due to the hot and humid climate of African region, Salius Pharma advises storing Aminophylline between 15–30°C in a dry, shaded place to maintain its stability. Reconstituted formulations should be tightly sealed and used within 7 days to ensure potency.
Salius Pharma ensures regulatory compliance by offering all essential documents including WHO-GMP certification, Drug Master File (DMF), Certificate of Analysis (CoA), and country-specific dossiers to support smooth registration with health authorities.
Yes, Aminophylline has a narrow therapeutic window and may interact with drugs such as caffeine, beta-blockers, and certain antibiotics. Monitoring blood levels is advised to avoid toxicity, and healthcare providers should be consulted before combining therapies, especially in African region where herbal supplements are commonly used.
Looking to source Aminophylline or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.