API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/USP/EP
C5H4N4O
1H-pyrazolo[3,4-d] pyrimidin-4-ol
315-30-0
136.1115 g/mol
Pyrazolo[3,4-d] pyrimidines
Antigout
| Appearance | White or almost white crystalline powder |
|---|---|
| Solubility | soluble in DMSO (3 mg/ml), poorly soluble in water (0.1 mg/mL) |
| Melting point | 320°C |
| pH | 3.1- 3.4 |
Allopurinol is a xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. Allopurinol is one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout.
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and xanthine to uric acid. The inhibition of this enzyme is responsible for the effects of allopurinol. This drug increases the reutilization of hypoxanthine and xanthine for nucleotide and nucleic acid synthesis by a process that involves the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRTase). This process results in an increased nucleotide concentration, which causes feedback inhibition of de novo purine synthesis. The end result is decreased urine and serum uric acid concentrations 15, which decreases the incidence of gout symptoms.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO-GMP, ISO 9001:2015, FDA-audited facilities |
| Affordability & Generic Access | Cost-competitive generics for global supply |
| Export Experience | Proven record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
In Latin America, Allopurinol is widely used to manage gout and hyperuricemia (high uric acid levels). It helps reduce the production of uric acid in the body, preventing gout attacks and complications such as kidney stones.
Yes, common side effects include skin rash, nausea, and drowsiness. In rare cases, more serious reactions can occur. It’s important to follow your doctor’s instructions and report any unusual symptoms.
Salius Pharma supplies Allopurinol as a bulk API (Active Pharmaceutical Ingredient). Upon request, we can also provide finished dosage forms such as tablets, tailored to the regulatory standards of Latin American markets.
To place an order, contact Salius Pharma with details such as required quantity, destination country in Latin America, and documentation needs like WHO-GMP certification, Certificate of Analysis, or Drug Master File (DMF). Our team will guide you through the process.
Salius Pharma supplies Allopurinol to several Latin American countries, including Peru, Ecuador, Bolivia, Guatemala, and the Dominican Republic, supporting local pharmaceutical production and formulation.
Looking to source Allopurinol or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.