API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/USP
C₄₄H₆₉NO₁₂
(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-12-[(E)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-1,14-dihydroxy-23-methoxy-13,15,17,19,21,27-hexamethyl-11,28-dioxa-4-azatricyclo[22.3.1.0^4,9]octacos-18-ene-2,3,10,16-tione
104987-11-3
804.02 g/mol
macrolide lactone immunosuppressants
| Appearance | White to off-white powder |
|---|---|
| Solubility | Poorly soluble in water; soluble in organic solvents like ethanol, methanol, DMSO |
| Melting point | ~129–131 °C |
| pH | ~ 4 to 6 |
Tacrolimus is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune diseases
Tacrolimus binds to the intracellular protein FKBP-12, forming a complex that inhibits calcineurin. This blocks the activation of T-cells by preventing the transcription of IL-2 and other cytokines, leading to immunosuppression.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Tacrolimus is generally more potent and has a lower risk of causing cosmetic side effects like gum hypertrophy and excessive hair growth compared to cyclosporine.
There is a theoretical risk due to immunosuppression, but current evidence is inconclusive. It carries a black box warning, so long-term use requires monitoring.
Tacrolimus has a narrow therapeutic window; levels too low risk rejection, too high-risk toxicity (especially kidney damage).
Salius Pharma supplies Tacrolimus as an Active Pharmaceutical Ingredient (API) and can also arrange finished dosage forms upon request
To order Tacrolimus API, you typically contact a certified pharmaceutical supplier like Salius Pharma. You’ll need to provide details such as desired quantity, intended market, regulatory requirements (e.g., DMF or GMP certificates), and packaging preferences.
Salius Pharma exports Tacrolimus to various countries worldwide, including regions such as Asia, Europe, the Middle East, Africa, North America & South America
Looking to source Tacrolimus or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.